Phf5a^tm1.1Oux
Targeted Allele Detail

Summary

• Symbol: Phf5a^tm1.1Oux
• Name: PHD finger protein 5A; targeted mutation 1.1, Xijun Ou
• MGI ID: MGI:7611699
• Gene: Phf5a Location: Chr15:81748717-81756093 bp, - strand Genetic Position: Chr15, 38.26 cM, cytoband E
• Alliance: Phf5a^tm1.1Oux page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:345807
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and an FRT-flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Flp-mediated recombination removed the neo cassette leaving exon 3 floxed. (J:345807)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Phf5a Mutation: 19 strains or lines available

References

• Original: J:345807 Zhang R, et al., Spliceosome component PHD finger 5A is essential for early B lymphopoiesis. Development. 2024 Jan 15;151(2):dev202247
• All: 1 reference(s)