Emc1^em1Xjz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Emc1^em1Xjz
• Name: ER membrane protein complex subunit 1; endonuclease-mediated mutation 1, Xianjun Zhu
• MGI ID: MGI:7611969
• Synonyms: Emc1^loxP
• Gene: Emc1 Location: Chr4:139079898-139106041 bp, + strand Genetic Position: Chr4, 70.66 cM
• Alliance: Emc1^em1Xjz page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9-mediated recombination using guide RNAs inserted loxP sites surrounding exons 5 and 6. (J:345827)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Emc1 Mutation: 56 strains or lines available

References

• Original: J:345827 Li X, et al., Deletion of Emc1 in photoreceptor cells causes retinal degeneration in mice. FEBS J. 2023 Sep;290(17):4356-4370
• All: 1 reference(s)