Armcx3^tm1.1Eso
Targeted Allele Detail

Summary

• Symbol: Armcx3^tm1.1Eso
• Name: armadillo repeat containing, X-linked 3; targeted mutation 1.1, Eduardo Soriano
• MGI ID: MGI:7612011
• Synonyms: Armcx3^fl, fARMCX3
• Gene: Armcx3 Location: ChrX:133657344-133662204 bp, + strand Genetic Position: ChrX, 56.25 cM
• Alliance: Armcx3^tm1.1Eso page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:345411
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin selection cassette and loxP site were inserted upstream of exon 5, which contains the coding sequence, and a second loxP site was inserted downstream of the coding sequence within exon 5. The neomycin selection cassette was removed leaving the coding sequence part of exon 5 floxed. (J:345411)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Armcx3 Mutation: 6 strains or lines available

References

• Original: J:345411 Mirra S, et al., ARMCX3 Mediates Susceptibility to Hepatic Tumorigenesis Promoted by Dietary Lipotoxicity. Cancers (Basel). 2021 Mar 5;13(5)
• All: 3 reference(s)