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Mldhrem1Zhgn
Endonuclease-mediated Allele Detail
Summary
Symbol: Mldhrem1Zhgn
Name: mitochondrial lactate dehydrogenase regulator; endonuclease-mediated mutation 1, Nu Zhang
MGI ID: MGI:7612218
Gene: Mldhr  Location: unknown  Genetic Position: Chr19, Syntenic
Alliance: Mldhrem1Zhgn page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR/cas9-mediated recombination created a 145 bp deletion. (J:303725)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mldhr Mutation:  0 strains or lines available
References
Original:  J:303725 Huang N, et al., An Upstream Open Reading Frame in Phosphatase and Tensin Homolog Encodes a Circuit Breaker of Lactate Metabolism. Cell Metab. 2021 Jan 5;33(1):128-144.e9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory