Cib3^em1Xuzg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cib3^em1Xuzg
• Name: calcium and integrin binding family member 3; endonuclease-mediated mutation 2, Zhigang Xu
• MGI ID: MGI:7612574
• Gene: Cib3 Location: Chr8:72958179-72966840 bp, - strand Genetic Position: Chr8, 34.88 cM
• Alliance: Cib3^em1Xuzg page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/cas9-mediated recombination created a 5,229 bp deletion, including exons 2 and 3. (J:345936)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cib3 Mutation: 12 strains or lines available

References

• Original: J:345936 Wang X, et al., CIB2 and CIB3 Regulate Stereocilia Maintenance and Mechanoelectrical Transduction in Mouse Vestibular Hair Cells. J Neurosci. 2023 May 3;43(18):3219-3231
• All: 1 reference(s)