Cand1^em1Zpan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cand1^em1Zpan
• Name: cullin associated and neddylation disassociated 1; endonuclease-mediated mutation 1, Zhenwei Pan
• MGI ID: MGI:7614261
• Gene: Cand1 Location: Chr10:119035160-119075960 bp, - strand Genetic Position: Chr10, 67.08 cM, cytoband D2
• Alliance: Cand1^em1Zpan page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Exons 3 to 7 were deleted. (J:345515)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cand1 Mutation: 52 strains or lines available

References

• Original: J:345515 Li X, et al., Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation. Pharmacol Res. 2022 Aug;182:106284
• All: 2 reference(s)