Tg(Myh6-Cand1)1Zpan
Transgene Detail

Summary

• Symbol: Tg(Myh6-Cand1)1Zpan
• Name: transgene insertion 1, Zhenwei Pan
• MGI ID: MGI:7614263
• Synonyms: CAND1-TG
• Transgene: Tg(Myh6-Cand1)1Zpan Location: unknown
• Alliance: Tg(Myh6-Cand1)1Zpan page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Cand1)1Zpan expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cand1 (MGI:1261820)

• Tg(Myh6-Cand1)1Zpan expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Myh6 (MGI:97255)

• Mutation details: The Myh6 (alpha-MHC) promotor drives the expression of mouse Cand1 cDNA. Three lines were generated. Line 1 has the highest level of expression. (J:345515)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:345515 Li X, et al., Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation. Pharmacol Res. 2022 Aug;182:106284
• All: 1 reference(s)