Mir409^em1Iclb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir409^em1Iclb
• Name: microRNA 409; endonuclease-mediated mutation 1, Basak Icli
• MGI ID: MGI:7616225
• Synonyms: miR-409-3p^fl, miR409^fl
• Gene: Mir409 Location: Chr12:109709592-109709670 bp, + strand Genetic Position: Chr12, 60.56 cM
• Alliance: Mir409^em1Iclb page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9-mediated recombination inserted loxP sites around the sole exon of the gene. (J:346294)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir409 Mutation: 0 strains or lines available

References

• Original: J:346294 Bestepe F, et al., Deficiency of miR-409-3p improves myocardial neovascularization and function through modulation of DNAJB9/p38 MAPK signaling. Mol Ther Nucleic Acids. 2023 Jun 13;32:995-1009
• All: 2 reference(s)