Pakap^tm1.1Div
Targeted Allele Detail

Summary

• Symbol: Pakap^tm1.1Div
• Name: paralemmin A kinase anchor protein; targeted mutation 1.1, Dario Diviani
• MGI ID: MGI:7618327
• Synonyms: AKAP2^fl
• Gene: Pakap Location: Chr4:57434475-57896984 bp, + strand Genetic Position: Chr4, 31.66 cM, cytoband C1
• Alliance: Pakap^tm1.1Div page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:345193
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 1 via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:345193)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pakap Mutation: 4 strains or lines available

References

• Original: J:345193 Maric D, et al., A-Kinase Anchoring Protein 2 Promotes Protection against Myocardial Infarction. Cells. 2021 Oct 23;10(11)
• All: 1 reference(s)