Rlbp1^tm1Kser
Targeted Allele Detail

Summary

• Symbol: Rlbp1^tm1Kser
• Name: retinaldehyde binding protein 1; targeted mutation 1, Philip Kiser
• MGI ID: MGI:7618777
• Gene: Rlbp1 Location: Chr7:79024618-79036796 bp, - strand Genetic Position: Chr7, 45.0 cM
• Alliance: Rlbp1^tm1Kser page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:10197
• Parent Cell Line: iTL BF1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Using conventional targeting by homologous recombination in ES cells, the allele was generated by inserting loxP sites flanking exon 6 followed by an frt-flanked neo-resistant cassette into the retinaldehyde binding protein 1 (Rlbp1) gene. The neo cassette was deleted during selected ES cell colony expansion through the action of FLP recombinase. (J:10197)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rlbp1 Mutation: 29 strains or lines available

References

• Original: J:10197 Natsuume-Sakai S, et al., Demonstration of an unusual allelic variation of mouse factor H by the complete cDNA sequence of the H.2 allotype. J Immunol. 1990 Jan 1;144(1):358-62
• All: 1 reference(s)