Greb1^em1Rkom
Endonuclease-mediated Allele Detail

Summary

• Symbol: Greb1^em1Rkom
• Name: gene regulated by estrogen in breast cancer protein; endonuclease-mediated mutation 1, Ramakrishna Kommagani
• MGI ID: MGI:7618841
• Gene: Greb1 Location: Chr12:16720616-16850887 bp, - strand Genetic Position: Chr12, 8.0 cM
• Alliance: Greb1^em1Rkom page

Mutation origin

• Strain of Origin: C57BL/6NJ

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 10 to 17. (J:346713)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Greb1 Mutation: 108 strains or lines available

References

• Original: J:346713 Chadchan SB, et al., A GREB1-steroid receptor feedforward mechanism governs differential GREB1 action in endometrial function and endometriosis. Nat Commun. 2024 Mar 2;15(1):1947
• All: 1 reference(s)