Cxcl11^em1Groj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cxcl11^em1Groj
• Name: chemokine (C-X-C motif) ligand 11; endonuclease-mediated mutation 1, Joanna R Groom
• MGI ID: MGI:7618973
• Synonyms: CXCL11^KI
• Gene: Cxcl11 Location: Chr5:92507403-92511155 bp, - strand Genetic Position: Chr5, 46.61 cM, cytoband E3
• Alliance: Cxcl11^em1Groj page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR/cas9 mediated recombination using an oligo donor restored expression of the full length protein. (J:345391)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cxcl11 Mutation: 6 strains or lines available

References

• Original: J:345391 Dalit L, et al., CXCL11 expressing C57BL/6 mice have intact adaptive immune responses to viral infection. Immunol Cell Biol. 2022 May;100(5):312-322
• All: 1 reference(s)