Zbtb22^em1Yga
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zbtb22^em1Yga
• Name: zinc finger and BTB domain containing 22; endonuclease-mediated mutation 1, Yong Gao
• MGI ID: MGI:7619075
• Gene: Zbtb22 Location: Chr17:34135150-34138299 bp, + strand Genetic Position: Chr17, 17.98 cM
• Alliance: Zbtb22^em1Yga page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology targeting exon 2 generated a knock-out allele. (J:344976)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zbtb22 Mutation: 24 strains or lines available

References

• Original: J:344976 Liu N, et al., Hepatic ZBTB22 promotes hyperglycemia and insulin resistance via PEPCK1-driven gluconeogenesis. EMBO Rep. 2023 Jun 5;24(6):e56390
• All: 1 reference(s)