Rnf123^em2Nmea
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf123^em2Nmea
• Name: ring finger protein 123; endonuclease-mediated mutation 2, Division of Experimental Animals Nagoya University
• MGI ID: MGI:7619961
• Gene: Rnf123 Location: Chr9:107928869-107957183 bp, - strand Genetic Position: Chr9, 59.07 cM
• Alliance: Rnf123^em2Nmea page

Mutation origin

• Strain of Origin: NC/Jic

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 397 bp deletion, deleting part of exon 2 to part of exon 3. (J:327312)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rnf123 Mutation: 60 strains or lines available

References

• Original: J:327312 Miyasaka Y, et al., E3 ubiquitin ligase RNF123-deficient mice exhibit reduced parasitemia and mortality in rodent malaria (Plasmodium yoelii 17XL) infection. Parasitol Int. 2022 Jun;88:102542
• All: 1 reference(s)