Gcc2^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gcc2^em1Cya
• Name: GRIP and coiled-coil domain containing 2; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7620191
• Gene: Gcc2 Location: Chr10:58091319-58141421 bp, + strand Genetic Position: Chr10, 29.3 cM, cytoband B3
• Alliance: Gcc2^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR/cas9 mediated recombination created a null allele. (J:346915)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gcc2 Mutation: 60 strains or lines available

References

• Original: J:346915 Tu X, et al., Interruption of post-Golgi STING trafficking activates tonic interferon signaling. Nat Commun. 2022 Nov 15;13(1):6977
• All: 1 reference(s)