Tnfsf18^em1Pwan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tnfsf18^em1Pwan
• Name: tumor necrosis factor (ligand) superfamily, member 18; endonuclease-mediated mutation 1, Ping Wang
• MGI ID: MGI:7621394
• Synonyms: Tnfsf18^f, Tnfsf18^flox
• Gene: Tnfsf18 Location: Chr1:161322224-161332859 bp, + strand Genetic Position: Chr1, 69.75 cM
• Alliance: Tnfsf18^em1Pwan page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 was flanked by loxP sites using CRISPR/Cas9 technology. (J:346395)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnfsf18 Mutation: 17 strains or lines available

References

• Original: J:346395 Li L, et al., GITRL impairs hepatocyte repopulation by liver progenitor cells to aggravate inflammation and fibrosis by GITR(+)CD8(+) T lymphocytes in CDE Mice. Cell Death Dis. 2024 Feb 6;15(2):114
• All: 1 reference(s)