Xrn1^em1.1Tya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Xrn1^em1.1Tya
• Name: 5'-3' exoribonuclease 1; endonuclease-mediated mutation 1.1, Tadashi Yamamoto
• MGI ID: MGI:7621400
• Gene: Xrn1 Location: Chr9:95836813-95939856 bp, + strand Genetic Position: Chr9, 50.31 cM, cytoband E4
• Alliance: Xrn1^em1.1Tya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRIPSR/cas9 mediated recombination inserted loxP sites flanking exons 2-6. Cre mediated recombination deleted exons 2-6. (J:342928)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Xrn1 Mutation: 79 strains or lines available

References

• Original: J:342928 Takaoka S, et al., Neuronal XRN1 is required for maintenance of whole-body metabolic homeostasis. iScience. 2021 Oct 22;24(10):103151
• All: 1 reference(s)