Sqor^em1Kkg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sqor^em1Kkg
• Name: sulfide quinone oxidoreductase; endonuclease-mediated mutation 1, Karen K Griffiths
• MGI ID: MGI:7621494
• Synonyms: SqordE6
• Gene: Sqor Location: Chr2:122607249-122651473 bp, + strand Genetic Position: Chr2, 60.67 cM, cytoband F2
• Alliance: Sqor^em1Kkg page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A 500 bp region encompassing exon 6 of the mouse Sqor gene was deleted in C57BL/6J embryos using CRISPR/cas9 methodologies. (J:347132)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sqor Mutation: 32 strains or lines available

References

• Original: J:347132 Griffiths KK, et al., Sulfide quinone oxidoreductase contributes to voltage sensing of the mitochondrial permeability transition pore. FASEB J. 2024 Feb 29;38(4):e23494
• All: 1 reference(s)