Npvf^tm1.1Ubu
Targeted Allele Detail

Summary

• Symbol: Npvf^tm1.1Ubu
• Name: neuropeptide VF precursor; targeted mutation 1.1, Takayoshi Ubuka
• MGI ID: MGI:7622046
• Gene: Npvf Location: Chr6:50627652-50631419 bp, - strand Genetic Position: Chr6, 24.34 cM, cytoband B3
• Alliance: Npvf^tm1.1Ubu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:347241
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 2 was flanked by loxP sites. An FRT-flanked neomycin selection cassette was inserted between exon 2 and the second loxP site and was removed via flp-mediated recombination. Mouse Npvf peptides, RFRP1 and RFRP3, are encoded in exon 2. (J:347241)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npvf Mutation: 5 strains or lines available

References

• Original: J:347241 Ubuka T, A mammalian gonadotropin-inhibitory hormone homolog RFamide-related peptide 3 regulates pain and anxiety in mice. Cell Tissue Res. 2023 Jan;391(1):159-172
• All: 1 reference(s)