Bpi^tm1.1Buls
Targeted Allele Detail

Summary

• Symbol: Bpi^tm1.1Buls
• Name: bactericidal permeablility increasing protein; targeted mutation 1.1, Sigrid Bulow
• MGI ID: MGI:7623758
• Gene: Bpi Location: Chr2:158100014-158126451 bp, + strand Genetic Position: Chr2, 78.72 cM
• Alliance: Bpi^tm1.1Buls page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:346703
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A genomic region spanning exons 3 and 4 was replaced with a floxed neo cassette via homologous recombination. Cre mediated recombination removed the neo cassette. (J:346703)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bpi Mutation: 27 strains or lines available

References

• Original: J:346703 Bulow S, et al., Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response. Cell Rep. 2024 Mar 26;43(3):113929
• All: 1 reference(s)