Magea4^em1Prp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Magea4^em1Prp
• Name: MAGE family member A4; endonuclease-mediated mutation 1, Patrick Ryan Potts
• MGI ID: MGI:7624339
• Gene: Magea4 Location: ChrX:71265623-71266570 bp, + strand Genetic Position: ChrX, 37.2 cM
• Alliance: Magea4^em1Prp page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR/cas9 mediated recombination using guide RNAs created an indel mutation and frameshift. This mutation is in cis with Magea10^em1Prp. (J:342299)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Magea4 Mutation: 6 strains or lines available

References

• Original: J:342299 Fon Tacer K, et al., MAGE cancer-testis antigens protect the mammalian germline under environmental stress. Sci Adv. 2019 May;5(5):eaav4832
• All: 1 reference(s)