Del(XMagea6-Magea1)1Prp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(XMagea6-Magea1)1Prp
• Name: deletion, Chr X, Patrick Ryan Potts 1
• MGI ID: MGI:7624347
• Synonyms: Mage-a delta6
• Gene: Del(XMagea6-Magea1)1Prp Location: unknown Genetic Position: ChrX, Syntenic

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intergenic deletion
• Del(XMagea6-Magea1)1Prp involves 9 genes/genome features (Magea6, Magea3, Gm6645 ...) View all
• CRISPR/cas9 mediated recombination created a 170 kb deletion removing 6 Magea genes. (J:342299)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(XMagea6-Magea1)1Prp Mutation: 0 strains or lines available

References

• Original: J:342299 Fon Tacer K, et al., MAGE cancer-testis antigens protect the mammalian germline under environmental stress. Sci Adv. 2019 May;5(5):eaav4832
• All: 1 reference(s)