About   Help   FAQ
Gm41261em1Geh
Endonuclease-mediated Allele Detail
Summary
Symbol: Gm41261em1Geh
Name: predicted gene, 41261; endonuclease-mediated mutation 1, Gregg E Homanics
MGI ID: MGI:7624349
Gene: Gm41261  Location: Chr15:6890929-6902168 bp, + strand  Genetic Position: Chr15, Syntenic
Alliance: Gm41261em1Geh page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR/Cas9 technology generated a 306 bp deletion in exon 1. RT-PCR confirmed the expression of a 306 bp smaller lncRNA in the cortex. Gm41261 is a natural antisense transcript to Osmr intron 1, however abundance of Osmr in the cortex is unaltered. (J:345829)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gm41261 Mutation:  0 strains or lines available
References
Original:  J:345829 Plasil SL, et al., Mutation of novel ethanol-responsive lncRNA Gm41261 impacts ethanol-related behavioral responses in mice. Genes Brain Behav. 2024 Feb;23(1):e12886
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory