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Gm41261em1Geh
Endonuclease-mediated Allele Detail
Summary
Symbol: Gm41261em1Geh
Name: predicted gene, 41261; endonuclease-mediated mutation 1, Gregg E Homanics
MGI ID: MGI:7624349
Gene: Gm41261  Location: Chr15:6890929-6902168 bp, + strand  Genetic Position: Chr15, Syntenic
Alliance: Gm41261em1Geh page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR/Cas9 technology generated a 306 bp deletion in exon 1. RT-PCR confirmed the expression of a 306 bp smaller lncRNA in the cortex. Gm41261 is a natural antisense transcript to Osmr intron 1, however abundance of Osmr in the cortex is unaltered. (J:345829)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gm41261 Mutation:  0 strains or lines available
References
Original:  J:345829 Plasil SL, et al., Mutation of novel ethanol-responsive lncRNA Gm41261 impacts ethanol-related behavioral responses in mice. Genes Brain Behav. 2024 Feb;23(1):e12886
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory