Tbc1d15^em1Jren
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tbc1d15^em1Jren
• Name: TBC1 domain family, member 15; endonuclease-mediated mutation 1, Jun Ren
• MGI ID: MGI:7626319
• Synonyms: tbc1d15^flox
• Gene: Tbc1d15 Location: Chr10:115033777-115087372 bp, - strand Genetic Position: Chr10, 63.51 cM
• Alliance: Tbc1d15^em1Jren page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR/cas9 mediated recombination using guide RNAs inserted loxP sites around exon 4. (J:341775)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbc1d15 Mutation: 106 strains or lines available

References

• Original: J:341775 Sun S, et al., TBC1D15-Drp1 interaction-mediated mitochondrial homeostasis confers cardioprotection against myocardial ischemia/reperfusion injury. Metabolism. 2022 Jun 6;134:155239
• All: 1 reference(s)