Gt(ROSA)26Sor^{em1(Tbc1d15)Jren}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{em1(Tbc1d15)Jren}
• Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Jun Ren
• MGI ID: MGI:7626321
• Synonyms: rosa26^CKI
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{em1(Tbc1d15)Jren} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{em1(Tbc1d15)Jren} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tbc1d15 (MGI:1913937)

• Mutation details: CRISPR/cas9 mediated recombination inserted a CAG-loxP-stop-loxP-Kozak-mouse Tbc1d15 CDS-polyA cassette into intron 1. (J:341775)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:341775 Sun S, et al., TBC1D15-Drp1 interaction-mediated mitochondrial homeostasis confers cardioprotection against myocardial ischemia/reperfusion injury. Metabolism. 2022 Jun 6;134:155239
• All: 1 reference(s)