Tg(CAG-cat,-Tcf25)1Xdgz
Transgene Detail

Summary

• Symbol: Tg(CAG-cat,-Tcf25)1Xdgz
• Name: transgene insertion 1, Xiao-Dong Zhang
• MGI ID: MGI:7628235
• Synonyms: CAG-CAT-Nulp1
• Transgene: Tg(CAG-cat,-Tcf25)1Xdgz Location: unknown
• Alliance: Tg(CAG-cat,-Tcf25)1Xdgz page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(CAG-cat,-Tcf25)1Xdgz expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tcf25 (MGI:1914105)

• Mutation details: A construct containing a CAG promoter diving expression of a floxed chloramphenicol acetyltransferase (cat) gene with a Poly A signal followed by a full length mouse Tcf25 cDNA was inserted. Cre mediated deletion of the cat gene allows for expression of the Tcf25 cDNA. (J:317382)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:317382 Zhang X, et al., NULP1 Alleviates Cardiac Hypertrophy by Suppressing NFAT3 Transcriptional Activity. J Am Heart Assoc. 2020 Aug 18;9(16):e016419
• All: 1 reference(s)