Ccdc50^em2Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ccdc50^em2Gpt
• Name: coiled-coil domain containing 50; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
• MGI ID: MGI:7638801
• Synonyms: Ccdc50^em1Cd
• Gene: Ccdc50 Location: Chr16:27207619-27270968 bp, + strand Genetic Position: Chr16, 18.98 cM
• Alliance: Ccdc50^em2Gpt page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 2-4. (J:345495)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccdc50 Mutation: 24 strains or lines available

References

• Original: J:345495 Hou P, et al., Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases. Cell Mol Immunol. 2021 Oct;18(10):2358-2371
• All: 1 reference(s)