Gucy2d^{em1(cre)Baccm}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gucy2d^{em1(cre)Baccm}
• Name: guanylate cyclase 2d; endonuclease-mediated mutation 1, Mark Baccei
• MGI ID: MGI:7639690
• Gene: Gucy2d Location: Chr7:98089623-98126685 bp, + strand Genetic Position: Chr7, 53.86 cM
• Alliance: Gucy2d^{em1(cre)Baccm} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Gucy2d^{em1(cre)Baccm} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gucy2d (MGI:106030)

• The cre recombinase gene was inserted into intron 1. (J:347977)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gucy2d (mouse) Summary of all recombinase alleles driven by Gucy2d. Alliance mouse Gucy2d gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gucy2d Mutation: 43 strains or lines available

References

• Original: J:347977 Serafin EK, et al., Development and characterization of a Gucy2d-cre mouse to selectively manipulate a subset of inhibitory spinal dorsal horn interneurons. PLoS One. 2024;19(3):e0300282
• All: 1 reference(s)