Abhd17a^em1Eko
Endonuclease-mediated Allele Detail

Summary

• Symbol: Abhd17a^em1Eko
• Name: abhydrolase domain containing 17A; endonuclease-mediated mutation 1, Eryan Kong
• MGI ID: MGI:7639938
• Gene: Abhd17a Location: Chr10:80419488-80426175 bp, - strand Genetic Position: Chr10, 39.72 cM
• Alliance: Abhd17a^em1Eko page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 mediated recombination using guide RNAs (GGCTCGCCTTGGACCGCGATGGG, TCACATGCAGTCCCGGCAGGAGG, and GAGCCATGTTCAGGCGTCAGAGG) created a 3176 bp deletion and a 7 bp deletion in the region spanning exons 2-5. (J:329241)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abhd17a Mutation: 18 strains or lines available

References

• Original: J:329241 Yan P, et al., Crosstalk of Synapsin1 palmitoylation and phosphorylation controls the dynamicity of synaptic vesicles in neurons. Cell Death Dis. 2022 Sep 12;13(9):786
• All: 1 reference(s)