Crx^rd23
Spontaneous Allele Detail

Summary

• Symbol: Crx^rd23
• Name: cone-rod homeobox; retinal degeneration 23
• MGI ID: MGI:7640120
• Gene: Crx Location: Chr7:15599872-15613880 bp, - strand Genetic Position: Chr7, 8.6 cM
• Alliance: Crx^rd23 page

Mutation origin

• Strain of Origin: B6;SJL-Tnfrsf14^tm1.1Kro/J

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Single point mutation
• Mutation details: This spontaneous single G to C point substitution in the splicing zone 5 base pairs after the end of exon 2, at Chr 7:15,605,064 (GRCm39), results in the loss of exon 2 and a frameshift that leads to a stop codon at amino acid 202. (J:348234)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Crx Mutation: 27 strains or lines available

References

• Original: J:348234 Chang B, The Crx spontaneous mutation. MGI Direct Data Submission. 2024;
• All: 1 reference(s)