Extl1^em1Caox
Endonuclease-mediated Allele Detail

Summary

• Symbol: Extl1^em1Caox
• Name: exostosin-like glycosyltransferase 1; endonuclease-mediated mutation 1, Xuetao Cao
• MGI ID: MGI:7641465
• Gene: Extl1 Location: Chr4:134083684-134099893 bp, - strand Genetic Position: Chr4, 66.63 cM
• Alliance: Extl1^em1Caox page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/cas9 mediated recombination using guide RNAs and a targeting vector inserted loxP sites around exons 2 and 3. (J:333437)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Extl1 Mutation: 41 strains or lines available

References

• Original: J:333437 Liu J, et al., Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity. Cell Rep. 2023 Jan 31;42(1):111991
• All: 1 reference(s)