Fbxw5^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fbxw5^em1Osb
• Name: F-box and WD-40 domain protein 5; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:7641837
• Gene: Fbxw5 Location: Chr2:25390762-25395482 bp, + strand Genetic Position: Chr2, 17.31 cM
• Alliance: Fbxw5^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted the coding sequence from exon to through a portion of exon 9 (3,076 bp). (J:348435)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbxw5 Mutation: 22 strains or lines available

References

• Original: J:348435 Suzuki A, et al., Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male mice. J Reprod Immunol. 2024;:104252
• All: 1 reference(s)