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Ppp1r42em1Osb
Endonuclease-mediated Allele Detail
Summary
Symbol: Ppp1r42em1Osb
Name: protein phosphatase 1, regulatory subunit 42; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI ID: MGI:7641912
Gene: Ppp1r42  Location: Chr1:10038849-10079361 bp, - strand  Genetic Position: Chr1, 2.25 cM, cytoband A2
Alliance: Ppp1r42em1Osb page
Mutation
origin
Strain of Origin:  (C57BL/6NJcl x DBA/2NJcl)F2
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR-targeting deleted the coding region of exon 2 through exon 7. (J:348447)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ppp1r42 Mutation:  29 strains or lines available
References
Original:  J:348447 Nguyen TTT, et al., Gene-deficient mouse model established by CRISPR/Cas9 system reveals 15 reproductive organ-enriched genes dispensable for male fertility. Frontiers in Cell and Developmental Biology. 2024;12
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory