Spz1^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spz1^em1Osb
• Name: spermatogenic leucine zipper 1; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:7641915
• Gene: Spz1 Location: Chr13:92711144-92712680 bp, - strand Genetic Position: Chr13, 47.75 cM, cytoband D1
• Alliance: Spz1^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted the coding region of exon 1. (J:348447)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Spz1 Mutation: 14 strains or lines available

References

• Original: J:348447 Nguyen TTT, et al., Gene-deficient mouse model established by CRISPR/Cas9 system reveals 15 reproductive organ-enriched genes dispensable for male fertility. Frontiers in Cell and Developmental Biology. 2024;12
• All: 1 reference(s)