Tg(Myh6-Dyrk1b)#Yax
Transgene Detail

Summary

• Symbol: Tg(Myh6-Dyrk1b)#Yax
• Name: transgene insertion, Xiaoxiang Yan
• MGI ID: MGI:7642197
• Synonyms: D1-Tg
• Transgene: Tg(Myh6-Dyrk1b)#Yax Location: unknown
• Alliance: Tg(Myh6-Dyrk1b)#Yax page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Dyrk1b)#Yax expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Dyrk1b (MGI:1330302)

• Tg(Myh6-Dyrk1b)#Yax expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Myh6

• The Myh6 promoter drives expression of a full-length mouse Dyrk1b transcript. (J:334531)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:334531 Zhuang L, et al., DYRK1B-STAT3 Drives Cardiac Hypertrophy and Heart Failure by Impairing Mitochondrial Bioenergetics. Circulation. 2022 Mar 15;145(11):829-846
• All: 1 reference(s)