Actc1dt^tm1Kwan
Targeted Allele Detail

Summary

• Symbol: Actc1dt^tm1Kwan
• Name: actin, alpha, cardiac muscle 1 divergent transcript; targeted mutation 1, Kun Wang
• MGI ID: MGI:7642224
• Synonyms: CPR^-
• Gene: Actc1dt Location: Chr2:113884877-113891986 bp, + strand Genetic Position: Chr2, 57.55 cM
• Alliance: Actc1dt^tm1Kwan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:297375
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A loxP flanked neomycin selection cassette replaced exons 1-2. (J:297375)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Actc1dt Mutation: 0 strains or lines available

References

• Original: J:297375 Ponnusamy M, et al., Long Noncoding RNA CPR (Cardiomyocyte Proliferation Regulator) Regulates Cardiomyocyte Proliferation and Cardiac Repair. Circulation. 2019 Jun 4;139(23):2668-2684
• All: 1 reference(s)