Tg(Myh6-Actc1dt)2Kwan
Transgene Detail

Summary

• Symbol: Tg(Myh6-Actc1dt)2Kwan
• Name: transgene insertion 2, Kun Wang
• MGI ID: MGI:7642226
• Synonyms: CPR Tg
• Transgene: Tg(Myh6-Actc1dt)2Kwan Location: unknown
• Alliance: Tg(Myh6-Actc1dt)2Kwan page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A 1906-bp fragment of mouse Actc1dt sequence is under the control of the alpha-myosin heavy chain (Myh6) promoter. Five lines (1-5) were generated. Line 2 shows about 4- to 5-fold increase in expression in neonatal and adult hearts. (J:297375)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:297375 Ponnusamy M, et al., Long Noncoding RNA CPR (Cardiomyocyte Proliferation Regulator) Regulates Cardiomyocyte Proliferation and Cardiac Repair. Circulation. 2019 Jun 4;139(23):2668-2684
• All: 1 reference(s)