Il1r2tm1.1Mchc
Targeted Allele Detail
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Symbol: |
Il1r2tm1.1Mchc |
Name: |
interleukin 1 receptor, type II; targeted mutation 1.1, Murray CH Clarke |
MGI ID: |
MGI:7643172 |
Synonyms: |
Il1r2fl |
Gene: |
Il1r2 Location: Chr1:40123872-40164390 bp, + strand Genetic Position: Chr1, 18.65 cM
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Alliance: |
Il1r2tm1.1Mchc page
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Germline Transmission: |
Earliest citation of germline transmission:
J:347877
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6NTac
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A loxP and F3-flanked neomycin selection cassette was inserted upstream of exon 3 and an FRT-flanked puromycin selection cassette and second loxP site were inserted downstream of exon 3. Flp-mediated recombination removed the selection cassettes leaving exon 3 floxed.
(J:347877)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Il1r2 Mutation: |
32 strains or lines available
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Original: |
J:347877 Pyrillou K, et al., Loss of T follicular regulatory cell-derived IL-1R2 augments germinal center reactions via increased IL-1. JCI Insight. 2024 Feb 8;9(5):e174005 |
All: |
1 reference(s) |
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