Psmd11^tm1.2Qit
Targeted Allele Detail

Summary

• Symbol: Psmd11^tm1.2Qit
• Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 11; targeted mutation 1.2, Tonggang Qi
• MGI ID: MGI:7643432
• Synonyms: PSMD11^delta
• Gene: Psmd11 Location: Chr11:80319441-80364074 bp, + strand Genetic Position: Chr11, 47.89 cM
• Alliance: Psmd11^tm1.2Qit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301736
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site and FRT-flanked neomycin selection cassette were inserted 220 bp downstream of exon 4 and a second loxP site was inserted 549 bp downstream of exon 5. The neomycin selection cassette was removed via flp-mediated recombination. Exon 5 was deleted via cre-mediated recombination in the germline. (J:301736)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Psmd11 Mutation: 41 strains or lines available

References

• Original: J:301736 Zhao L, et al., Generation and identification of a conditional knockout allele for the PSMD11 gene in mice. BMC Dev Biol. 2021 Feb 1;21(1):4
• All: 1 reference(s)