Rnf149^em1Staa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf149^em1Staa
• Name: ring finger protein 149; endonuclease-mediated mutation 1, Ariel Stanhill
• MGI ID: MGI:7643433
• Gene: Rnf149 Location: Chr1:39590377-39616486 bp, - strand Genetic Position: Chr1, 18.33 cM
• Alliance: Rnf149^em1Staa page

Mutation origin

• Strain of Origin: (BALB/c x C57BL/6)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 mediated recombination using guide RNAs targeting exons 1 and 5 created a 19 kb deletion spanning from exon 1 to exon 5. (J:335358)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf149 Mutation: 12 strains or lines available

References

• Original: J:335358 Legesse A, et al., The role of RNF149 in the pre-emptive quality control substrate ubiquitination. Commun Biol. 2023 Apr 8;6(1):385
• All: 1 reference(s)