Il31^tm1.1Ysfk
Targeted Allele Detail

Summary

• Symbol: Il31^tm1.1Ysfk
• Name: interleukin 31; targeted mutation 1.1, Yoshinori Fukui
• MGI ID: MGI:7643916
• Gene: Il31 Location: Chr5:123618215-123620686 bp, - strand Genetic Position: Chr5, 63.0 cM, cytoband F
• Alliance: Il31^tm1.1Ysfk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:305132
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: Enhanced green fluorescent protein (EGFP) and an FRT-flanked neomycin-resistance cassette were inserted immediately after the initiation codon. The neomycin cassette was removed via flp-mediated recombination. (J:305132)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il31 Mutation: 13 strains or lines available

References

• Original: J:305132 Sakata D, et al., Selective role of neurokinin B in IL-31-induced itch response in mice. J Allergy Clin Immunol. 2019 Oct;144(4):1130-1133.e8
• All: 1 reference(s)