Mrpl12^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mrpl12^em1Smoc
• Name: mitochondrial ribosomal protein L12; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7645355
• Synonyms: Mrpl12^{em1(flox)Smoc}
• Gene: Mrpl12 Location: Chr11:120375463-120379580 bp, + strand Genetic Position: Chr11, 84.18 cM, cytoband E2
• Alliance: Mrpl12^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9 mediated recombination inserted loxP sites around exons in the gene. (J:339098)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mrpl12 Mutation: 16 strains or lines available

References

• Original: J:339098 Ji X, et al., MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells. iScience. 2023 May 19;26(5):106656
• All: 1 reference(s)