Dkk4^em1(cre)Baz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dkk4^em1(cre)Baz
• Name: dickkopf WNT signaling pathway inhibitor 4; endonuclease-mediated mutation 1, Hisham Bazzi
• MGI ID: MGI:7645459
• Synonyms: Dkk4^tm1(Cre)Baz
• Gene: Dkk4 Location: Chr8:23114059-23117563 bp, + strand Genetic Position: Chr8, 11.42 cM
• Alliance: Dkk4^em1(cre)Baz page

Mutation origin

• Strain of Origin: FVB/NRj

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Dkk4^em1(cre)Baz expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Dkk4 (MGI:2385299)

• CRISPR-targeting inserted the cre recombinase gene before the ATG start site. (J:347581)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Dkk4 (mouse) Summary of all recombinase alleles driven by Dkk4. Alliance mouse Dkk4 gene page

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dkk4 Mutation: 14 strains or lines available

References

• Original: J:347581 Khatif H, et al., Generation and characterization of a Dkk4-Cre knock-in mouse line. Genesis. 2024 Feb;62(1):e23532
• All: 1 reference(s)