Tmem241^em1Blsg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmem241^em1Blsg
• Name: transmembrane protein 241; endonuclease-mediated mutation 1, Bao-Liang Song
• MGI ID: MGI:7645535
• Gene: Tmem241 Location: Chr18:12113193-12254604 bp, - strand Genetic Position: Chr18, 5.98 cM
• Alliance: Tmem241^em1Blsg page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/cas9 mediated recombination targeting exons 6-10 created a null allele. (J:344360)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem241 Mutation: 52 strains or lines available

References

• Original: J:344360 Zhao N, et al., TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport. J Lipid Res. 2023 Oct 27;64(12):100465
• All: 1 reference(s)