Eif4a1^tm1.1Bea
Targeted Allele Detail

Summary

• Symbol: Eif4a1^tm1.1Bea
• Name: eukaryotic translation initiation factor 4A1; targeted mutation 1.1, Douglas Strathdee
• MGI ID: MGI:7646942
• Synonyms: Eif4a1^tm2cBea
• Gene: Eif4a1 Location: Chr11:69557762-69563249 bp, - strand Genetic Position: Chr11, 42.86 cM
• Alliance: Eif4a1^tm1.1Bea page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:344730
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 2 - 4 were floxed and an FRT flanked selection cassette was inserted via homologous recombination. Flp mediated recombination removed the selection cassette. (J:344730)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eif4a1 Mutation: 17 strains or lines available

References

• Original: J:344730 Screen M, et al., RNA helicase EIF4A1-mediated translation is essential for the GC response. Life Sci Alliance. 2024 Feb;7(2)
• All: 1 reference(s)