Eif4b^tm1.1Tnr
Targeted Allele Detail

Summary

• Symbol: Eif4b^tm1.1Tnr
• Name: eukaryotic translation initiation factor 4B; targeted mutation 1.1, Martin Turner
• MGI ID: MGI:7646946
• Synonyms: Eif4b^tm1Tnr
• Gene: Eif4b Location: Chr15:101982208-102005608 bp, + strand Genetic Position: Chr15, 57.26 cM
• Alliance: Eif4b^tm1.1Tnr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:344730
• Parent Cell Line: C2J (ES Cell)
• Strain of Origin: B6(Cg)-Tyr^c-2J/J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 3 - 4 were floxed and an FRT flanked selection cassette inserted via homologous recombination. Flp mediated recombination removed the selection cassette. (J:344730)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eif4b Mutation: 47 strains or lines available

References

• Original: J:344730 Screen M, et al., RNA helicase EIF4A1-mediated translation is essential for the GC response. Life Sci Alliance. 2024 Feb;7(2)
• All: 1 reference(s)