Fsip1^em1Nali
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fsip1^em1Nali
• Name: fibrous sheath-interacting protein 1; endonuclease-mediated mutation 1, Na Li
• MGI ID: MGI:7647189
• Gene: Fsip1 Location: Chr2:117960905-118087447 bp, - strand Genetic Position: Chr2, 59.38 cM, cytoband E5
• Alliance: Fsip1^em1Nali page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• Mutation details: CRISPR/Cas9 technology targeting exon 3 generated a knock-out allele. Western blot analysis confirmed absence of testicular protein expression. (J:333257)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fsip1 Mutation: 22 strains or lines available

References

• Original: J:333257 Gamallat Y, et al., Bi-allelic mutation in Fsip1 impairs acrosome vesicle formation and attenuates flagellogenesis in mice. Redox Biol. 2021 Jul;43:101969
• All: 1 reference(s)