Ube4b^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ube4b^em1Bcgen
• Name: ubiquitination factor E4B; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7647232
• Synonyms: Ube4b^flox
• Gene: Ube4b Location: Chr4:149412873-149511206 bp, - strand Genetic Position: Chr4, 79.08 cM
• Alliance: Ube4b^em1Bcgen page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting inserted loxP sites into intron 2 and intron 4. (J:332423)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ube4b Mutation: 75 strains or lines available

References

• Original: J:332423 Kong X, et al., Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development. Development. 2022 Dec 15;149(24):dev201286
• All: 1 reference(s)