Mylk4^em2Yima
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mylk4^em2Yima
• Name: myosin light chain kinase family, member 4; endonuclease-mediated mutation 2, Yuuki Imai
• MGI ID: MGI:7647257
• Gene: Mylk4 Location: Chr13:32884810-32967937 bp, - strand Genetic Position: Chr13, 13.72 cM
• Alliance: Mylk4^em2Yima page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated an 11 bp (CGCTCCATTTG) deletion in exon 3. (J:316008)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mylk4 Mutation: 30 strains or lines available

References

• Original: J:316008 Sakakibara I, et al., Myofiber androgen receptor increases muscle strength mediated by a skeletal muscle splicing variant of Mylk4. iScience. 2021 Apr 23;24(4):102303
• All: 1 reference(s)