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Rnf122em1Caox
Endonuclease-mediated Allele Detail
Summary
Symbol: Rnf122em1Caox
Name: ring finger protein 122; endonuclease-mediated mutation 1, Xuetao Cao
MGI ID: MGI:7647313
Gene: Rnf122  Location: Chr8:31601848-31621510 bp, + strand  Genetic Position: Chr8, 17.97 cM
Alliance: Rnf122em1Caox page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR/cas9 mediated recombination using guide RNAs created a 157 bp deletion of exon 2. (J:344769)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rnf122 Mutation:  15 strains or lines available
References
Original:  J:344769 Wang W, et al., RNF122 suppresses antiviral type I interferon production by targeting RIG-I CARDs to mediate RIG-I degradation. Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9581-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory